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Prevention and Early Detection

About

There are a wide range of reasons why patients get kidney disease. It may be because of diabetes, high blood pressure, a hereditary condition, medications or dyes used in medical procedures that can damage the kidneys. Prevention and early detection is important to prevent kidney disease. Research into understanding detection through blood and urine tests, effects of medications on the kidneys and biology of kidney damage from various conditions could prevent and detect damage to the kidneys at an early stage.

Publications and Presentations

Publications

  • Aeng, ESY, Shalansky, KF, Lau, TTY, Zalunardo, N, Li, GY, Bowie, WR, Duncan, CP. (2015). Acute Kidney Injury With Tobramycin-Impregnated Bone Cement Spacers in Prosthetic Joint Infections. Annals of Pharmacotherapy, 49(11), 1207-1213.
  • Graziani MS, Plebani M. (2015). The standardization of the urine albumin assays: no longer deferrable. Clinical Chemistry and Laboratory Medicine (CCLM). 53(11):1657-9.
  • Hemmett J, Er L, Chiu HH, Cheung C, Djurdjev O, Levin A. (2015). Time to revisit the problem of CIN? The low incidence of acute kidney injury with and without contrast in hospitalized patients: an observational cohort study. Canadian journal of kidney health and disease. 2(1):1-8.
  • Jacobson BE, Seccombe DW, Katayev A, Levin A. (2015). A study examining the bias of albumin and albumin/creatinine ratio measurements in urine. Clinical Chemistry and Laboratory Medicine (CCLM). 2015 Mar 28
 
  • Chau, K, Schisler, T, Er, L, Jaswal, D, Cheung, C, Israel, A, Bowering, J, Levin, A. (2014). Fluid balance, change in serum creatinine  ,urine output as markers of acute kidney injury post cardiac surgery: an observational study. Can J Kidney Health Dis, 1, 19.
  • Grunau BE, Pourvali R, Wiens MO, Levin A, Li J, Grafstein E, Joo D, Scheuermeyer FX. (2014). Characteristics and Thirty‐day Outcomes of Emergency Department Patients With Elevated Creatine Kinase. Academic Emergency Medicine. 21(6):631-6.
  • Hutton, HL, DeMarco, ML, Magil, AB, Taylor, P. (2014). Renal Leukocyte Chemotactic Factor 2 (LECT2) Amyloidosis in First Nations People in Northern British Columbia, Canada: A Report of 4 Cases. American Journal of Kidney Diseases. (645): 790-792.
  • Kendrick JG, Ensom MHH, Steer A, White CT, Kwan E, Carr RR. Standard-Dose Versus High-Dose Acyclovir in Children Treated Empirically for Encephalitis: A Retrospective Cohort Study of Its Use and Safety. Pediatric Drugs. Volume 16, Number 3 (2014): Pages 229-234
  • Levin A, Remuzzi G. (2014). Clinical trials: ISN-ACCTS: global initiatives to improve clinical research. Nature Reviews Nephrology. 2014 Aug 1;10(8):426-7.
  • Levin A. (2014). Commentary on “Kidney disease guideline profusion and confusion:  unintended consequences of different perspectives and definitions”, AJKD, May 2014; Vol 63, Issue 5, pp 749-52
  • Levin, A, Remuzzi, G. (2014). CLINICAL TRIALS ISN-ACCTS: global initiatives to improve clinical research. Nature Reviews Nephrology, 10(8), 426-427.
  • Levin, A, Stevens, PE, Coresh, J, Levey, A. (2014). Screening, Monitoring, and Treatment of Stage 1 to 3 Chronic Kidney Disease. Annals of Internal Medicine, 161(1), 81-82.
  • Linder, A, Fjell, C, Levin, A, Walley, KR, Russell, JA, Boyd, JH. (2014). Small Acute Increases in Serum Creatinine Are Associated with Decreased Long-Term Survival in the Critically Ill. American Journal of Respiratory and Critical Care Medicine. 189(9): 1075-1081.
  • Misra, S, Gupta, A, Symes, A, Duncan, J. (2014). Haemophagocytic syndrome after intravesical bacille Calmette-Guerin instillation. Scandinavian Journal of Urology, 48(3), 328-330
  • AlAbbas A, Campbell AI, Skippen P, Human D, Matsell DG,Mammen C. Epidemiology of cardiac surgery associated acute kidney injury in neonates: A retrospective study. Pediatric Nephrology. 28:1127-34.
  • Coresh J, Levey AS, Levin A, Stevens P. (2013). A stable definition of chronic kidney disease improves knowledge and patient care. BMJ. 347.
  • Eckardt, KU, Coresh, J, Devuyst, O, Johnson, RJ, Kottgen, A, Levey, AS, Levin, A. (2013). Evolving importance of kidney disease: from subspecialty to global health burden. Lancet. 382(9887) 158-169.
  • Imani PD, Odiit A, Hingorani SR, Weiss NS, Eddy AA. Acute kidney injury and its association with in-hospital mortality among children with acute infections. Pediatr Nephrol. 28:2199-2206.
  • Lafrance, JP, Levin, A. (2013). Defining AKI: closer to getting the math right. Nephrology Dialysis Transplantation, 28(6), 1340-1342.
  • Levey, AS, Levin, A, Kellum, JA. (2013). Definition and Classification of Kidney Diseases. American Journal of Kidney Diseases, 61(5), 686-688.
  • Levin, A, Lancashire, W, Fassett, RG. (2013). Targets, trends, excesses,  ,deficiencies: refocusing clinical investigation to improve patient outcomes. Kidney International, 83(6), 1001-1009.
  • Levin, A, Perkovic, V. (2013). EPIDEMIOLOGY Global Burden of Disease Study 2010: implications for nephrology. Nature Reviews Nephrology, 9(4), 195-197.(6), 1001-1009
 
  • Bagshaw S, Wald R, Barton J, Burns K, Friedrich J, House A, James M, Levin A, Moist L, Pannu N, Stollery D, Walsh M. Clinical factors associated with inititation of renal replacement therapy in critically ill patients with Acute Kidney Injury – a prospective multi-centre observational study journal of critical care. Journal of Critical Care. June 2012; 27(3):268-75.
  • Iosfina J, Lan J, Chan C, Levin A. Massive Colchicine Overdose with Recovery.Case Reports in Nephrology and Urology, Jan-Jun 2012; 2:20-4.
  • Levin A. (2012). Year in Review 2011 - Progression, prediction, populations and possibilities. Nature Reviews Nephrology, Feb 2012; 8(2)70-2.  
  • Molitoris B, Okusa M, Palevsky P, Chawla L, Kaufman J, Devarajan P, Toto R, Hsu C-Y, Greene T, Faubel S, Kellum J, Wald R, Chertow G, Levin A, et al. Design of Clinical Trials in Acute Kidney Injury: A Report from an NIDDK Workshop. Trials of patients with sepsis and in selected hospital settings. CJASN May 2012; 7(5):856-60.
  • Okusa M, Molitoris B, Palevsky P, Chinchilli V, Liu K, Cheung A, Weisbord D, Faubel S, Kellum J, Wald R, Chertow G, Levin A et al. Design of clinical trials in Acute Kidney Injury: a Report from an NIDDK Workshop-Prevention Trials. CJASN May 2012; 7(5):851-5.
  • Palevsky P, Molitoris B, Okusa M, Faubel S, Kellum J, Wald R, Chertow G, Levin A, et al. Design of Clinical Trials in Acute Kidney Injury: Report from an NIDDK Workshop on Trial Methodology. CJASN May 2012; 7(5):844-50.
  • Trnka P, Hiatt MJ, Tarantal AF, Matsell DG. (2012). Congenital urinary tract obstruction: defining markers of developmental kidney injury. Pediatric Research. 72:446-454.  
  • Trnka P, Ivanova L, Hiatt MJ, Milner R, Matsell DG. Urinary biomarkers in obstructive nephropathy.Clinical Journal of the American Society of Nephrology. 7:1567-1575
 
 
  • Negash DT, Dhingra VK, Copland M, Griesdale D, Henderson W. Intensity of continuous renal replacement therapy in acute kidney injury in the intensive care unit: a systematic review and meta-analysis. Vascular and Endovascular Surgery. 2011 Aug; 45(6):504-10.
  • Prestidge C, Rassekh SR, Matsell DG. Nephrotic syndrome developing during induction chemotherapy for childhood acute lymphoblastic leukemia. Clinical and Experimental Nephrology. 2011 Jun; 15(3):410-3
  • Jia Y, Sun YH, House JD, Ogborn MR, Weiler HA, O K, Aukema HM. Long-term intake of whole proteins results in renal damage in the pig model. J Nutr. 140(9):1646-52, 2010.
  • Levin A. (2010). Health care reform, US and Canada: Musings as to myths and caveats. Renal and Urology News. June 2010.
  • Trnka P, Hiatt MJ, Ivanova L, Tarantal AF, Matsell DG. (2010). Phenotypic transition of the collecting duct epithelium in congenital urinary tract obstruction. Journal of Biomedicine and Biotechnology. 2010:696034. 
  • Warnock DG, Remuzzi G, Brenner BM, Levin A, Wanner C. (2010). Introduction to focus on Fabry nephropathy: Biomarkers, progression, and disease severity. Clinical Journal of the American Society of Nephrology. 5(2):359
 

Presentations

 
 

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